ICU AND YOU · Superpuzzle #47 — Transplantation Medicine

Type straight into the grid — click a square or a clue to start, and the letters will advance for you. Nothing is saved, so finish in one sitting and press Send my answers when you are done. Everything here is answerable from this week's mind map, or from a transplant patient you have already looked after. Two of the fifteen are historical, and one is breakfast.

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On a phone, scroll the grid sideways. Arrow keys move; typing a letter moves you on; backspace steps back.

Across

4the enzyme that tacrolimus and cyclosporin inhibit
6what the transplanted heart is … which is why atropine is useless
11electrolyte emergency of the post-reperfusion syndrome
12prophylaxis against pneumocystis, important for transplant recipients
13this virus is the driver behind post-transplant lymphoproliferative disease (two words)
14mould that finds the immunosuppressed lung at months 1 to 6 post-transplant of any organ
15“…… hyperplasia” — the cyclosporin complication the dentist spots first

Down

1organ grafted between two members of the same species
2antifungal that can treble a tacrolimus level overnight
3Dutch city lending its name to the five categories of donation after circulatory death
5expected resting finding in the transplanted heart, vagal tone having gone
7urgent bedside study when a liver recipient's lactate starts rising
8calcineurin inhibitor's neurological complication, posterior and reversible (initials)
9“Louis ……” the first heart transplant recipient, who lived eighteen days postop
10breakfast juice that raises calcineurin inhibitor levels

Sending your answers

Finish it, or get as far as you get — partial sets are welcome and are how I find out which clue was unfair. The button collects whatever you have typed and puts it into an email to me.

If the button does nothing on your device, screenshot the grid and send it to icuandyou@icloud.com instead.